DASH Diet Versus Intermittent Fasting on Insulin Resistance in NAFLD Patients

Abstract

objectives: To compare between intermittent fasting and DASH diet on glycemic profile in non-alcoholic fatty liver patients. Methods:60 (men and women) prediabetic nonalcoholic fatty liver patients participated in this study; assigned randomly to three groups: Group (A): intermittent fasting time-restricted feeding (TRF) subjects consumed 100 % of their energy needs in an 8 hours period of time each day, with their caloric intake divided into three meals consumed at 1 p.m., 4 p.m., and 8 p.m. schedule (8-hr daily eating period, the remaining 16 hours per 24-hour period made up the fasting period). Group (B): the dietary approach to stop hypertension (DASH) subjects consumed 100 % of their energy needs divided into three meals consumed at 8 a.m., 1 p.m., and 8 p.m. (12-hr eating period). Group (C): control group; all subjects didn’t follow any diet regimen or calorie deficit. all participants subjected to 30 minutes moderate aerobic exercise on treadmill. Subjects tested before and after 8 weeks of the study. Results: The nonalcoholic fatty liver patients in Group B received DASH diet program more improved fasting glucose reduction percentage (18.25%), followed by patients in Group A (14.79%) received intermittent fasting program, and then those in Group C (2.55%) control group & Group B received DASH diet program more improved HOMA IR reduction percentage (62.88%), followed by patients in Group A (45.23%) received intermittent fasting program, and then those in Group C (6.77%) received control group. Conclusion; both Dash & IF are effective therapeutic approach to control insulin resistance in NAFLD patients, prevention strategy for diabetes type 2.