Effectiveness of laser radiance on Morganella morganaii secluded from malignant tumors (cancer)

Abstract

Objective: The aim of this research to affect study radiation emitted from Nd: YAG laser  on Morganella morgana isolated from malignant tumors. Study design: Case –Control study design in Analytical study design by 15 isolates from malignant tumors compared with 15 isolates from normal person. Cross-Sectional study design in descriptive study design for 30 isolates. Backrgound: Morganella morganii is a fermissive anaerobic rod Gram-negative enteric bacterium that was headmost isolated in 1906 via Morgan et al. of a pediatric fecal culture. Cancer evolution is the result of a spectrum of genetic modifications that change the normal control of cell expansion and survival. These genetic modifications can be enhanced by a wide diversity of external factors  inclusive smoking, alcohol  and sunlight. Methodology: Morganella morganii implanted in Nutrient broth  at 37° C for 24 h  and rapprochement with MacCfrland 0.5, subsequently exposing 1 ml of suspension to Nd:YAG laser with comparison of control group (without exposure to radiance), each run was done in triplicate and inoculated in Trypton soy agar.  Results: Results the collection from sample are 15 isolates of Morganella morganii from patient malignant tumors and 15 isolates from healthy human. The results in this research proved a high rate of killing of bacteria  Morganella morganii isolated from malignant tumors after exposure to Nd:YAG laser during 500 pulses per second and the number of live cells was few after exposure to the laser at different times and the more time the higher the killing rate compared to the control of samples not exposed to the laser as well as with repeaters and that.  The use of Nd:YAG laser is secure, as it is utilized in cosmetics and there are no side impacts, so the competence of killing Morganella morganii secluded of cancer utilizing secure laser with high competence is very significant and it is an substantial application for treatment. Conclusion: The use of laser is safe as it is used in cosmetics and there are no side effects, and thus the efficiency of killing bacteria isolated from cancer using a safe laser with high efficiency is very important and it is an important application for treatment.