Pharmaceutical And Analytical Study Of Shunthyadi Kwath

Abstract

Shunthyadi Kwath is a traditional Ayurvedic polyherbal decoction recognized for its therapeutic efficacy in managing digestive, respiratory, and inflammatory disorders. This study aims to evaluate the pharmaceutical quality and safety profile of Shunthyadi Kwath through a detailed analytical investigation. A sample, described as a brown liquid in a sealed plastic bottle, was subjected to physicochemical, chemical, and microbiological analyses at Qualichem Laboratories, Nagpur, from 25 May 2024 to 3 June 2024. Key parameters included specific gravity (1.0182), total solids (3.81% w/w), pH (4.98), heavy metal content (lead: 0.327 mg/kg, arsenic: 0.162 mg/kg, mercury: 0.116 mg/kg, cadmium: below quantification limit), total phenolic content (0.09% w/v equivalent to tannic acid), and aflatoxin levels (below detection limit of 0.001 ppm). Microbiological tests confirmed a total microbial count of 220 cfu/ml, yeast and mold count below 10 cfu/ml, and the absence of pathogens such as Escherichia coli, Salmonella, Staphylococcus aureus, and Pseudomonas aeruginosa. High-Performance Thin-Layer Chromatography (HPTLC) profiling ensured chemical consistency. These results validate the safety, quality, and conformity of Shunthyadi Kwath to Ayurvedicpharmacopoeial requirements, thereby making it a suitable drugfor therapeutic administration and marking its merit for future pharmacological exploration.