THE EFFECT OF SUBCONJUNCTIVAL RESVERATROL INJECTION ON IL-6 AND TNF-Α EXPRESSION ON FORM DEPPRIVATION MYOPIA

Abstract

This paper explores the relationship between inflammation and myopia, a prevalent refractive error with increasing global prevalence, particularly in Asia. It discusses the role of inflammatory cytokines, such as IL-6 and TNF-α, in the pathophysiology of myopia, highlighting evidence that myopic eyes exhibit elevated levels of these cytokines compared to non-myopic eyes. The review examines various studies that demonstrate how inflammation may contribute to ocular elongation and the progression of myopia through mechanisms involving the scleral extracellular matrix and immune cell activity. Additionally, the potential therapeutic effects of resveratrol, a polyphenolic compound with anti-inflammatory properties, are considered in the context of form deprivation myopia. The findings suggest that targeting inflammatory pathways may offer novel strategies for managing myopia and mitigating its rising incidence worldwide.