Community-Based Development of Riceberry Extract-based Health Products: A Model for Sustainable Agriculture and Public Health

Abstract

This study investigates the development of health product prototypes using Riceberry extract for cosmetics, including matte lipstick, sunscreen, serum, and encapsulated products. The research assessed product retention, irritation, and efficacy through a series of tests involving raw material selection, extract preparation, and cell toxicity evaluations. The inhibition of melanin production in melanoma cells (B16F10) was also examined, followed by formula development and safety assessments. Toxicity testing showed that Riceberry extract and Kojic acid, at concentrations ranging from 0.0001 to 1 mg/ml, were non-toxic to melanoma cells, with survival rates of 96.29±2.59% and 97.39±1.38%, respectively. At 1 mg/ml, Riceberry extract reduced melanin production by 20.60±3.67% without affecting tyrosinase synthesis in melanoma cells. Among the sunscreen, peel-off mask, and encapsulation formulations, Formula 4 demonstrated the highest stability, maintaining a pH of 4.44 and showing no delamination under accelerated conditions. While some volunteers experienced mild irritation, statistical analysis revealed significant pH changes before and after freeze-thaw cycles. The study concluded that the products were stable, effective, and safe for use. Furthermore, the development of Riceberry extract-based health products holds potential for adding value, creating job opportunities, and supporting agricultural careers, particularly for rice farmers. Community engagement played a crucial role in the success of the product development process, with active public participation in the co-creation of prototypes.