Photoinduced Antifungal Studies of Functionally Modified Beta Cyclodextrin- Carbon Nanoparticle System

Abstract

paper describes the synthesis of carbon nanoparticle (CNP) from natural sources such as kitchen soot, synthesise of a chromophoric system {5-[4-(dimethylamino) benzylidene]-4-oxo-2-thioxo1, 3-thiazolidin-3-yl} acetic acid and its incorporation into β- cyclodextrin (β-CD) through the esterification of the hydroxyl group with the free carboxyl function of the chromophoric system by DCC coupling. Encapsulation of CNP in to functionally modified β-CD system was achieved. Characterization of the products was undertaken by UV-visible, FT-IR, NMR, fluorescence spectroscopic methods, SEM, TEM, and X-ray diffraction methods. It is also aimed to study the thermal stability, light fastening ability and photoinduced antifungal action of the products. The antifungal activity of functionally modified CD-CNP systems was tested against pathogenic fungal strain such as Aspergillus niger, Aspergillus fumigates, Aspergillus flavus, Penicillium janthinellum and Mucor ramosissimus by well method. The results showed that and functionally modified product have excellent photoinduced antifungal activity against selected fungal strains.