Extraction and physiochemical evaluation of Randia dumetorumroots & leaves

Abstract

"Randia dumetorum, commonly known as the emetic nut or 'Mainphal,' is a medium-sized shrub native to tropical and subtropical regions of Asia. This plant, belonging to the Rubiaceae family, has been traditionally used in Ayurveda for treating ailments such as fever, gastrointestinal disorders, and skin diseases. Present paper deals with preliminary pharmacognostic and physicochemical evaluation of roots & leaves of Randia dumetorum Lamk., to establish authenticity and possibly to help to distinguish drug from other species. The study includes preparation of different extracts by successive solvent extraction for detailed analysis. Different physicochemical parameters were carried out as per WHO recommended physicochemical determinations and authentic phytochemical procedures. Preliminary qualitative chemical test for different extract shows the presence of Glycosides, Carbohydrates,Phytosterols/triterpenoids, Saponins, Fixed oils & Fats and phenolic/tannins. Also, acute toxicity studies has been carried out as per Organization for Economic co-operation and Development (OECD) guidelines.