Adherence to Antihypertensive Medications Among Patients with Chronic Kidney Disease in Saudi Arabia: A Single-Center Experience Running title: Adherence to antihypertensive medications in chronic kidney disease patients

Authors

  • Muthana Al Sahlawi MD

DOI:

https://doi.org/10.70135/seejph.vi.3442

Abstract

Background: Hypertension is highly prevalent among patients with chronic kidney disease (CKD), and is a leading cause of CKD progression, cardiovascular events, and mortality. Adherence to antihypertensive medications is important in maintaining
blood pressure (BP) control, and reducing its related complications. Objectives: To assess the adherence to antihypertensive medication among patients with CKD, and to explore the reasons of nonadherence. Material and methods: This was a cross‑sectional, retrospective study examining the rates and reasons of nonadherence to antihypertensive medication among adult patients with predialysis CKD at a large tertiary hospital in Saudi Arabia. Data were analyzed using SAS Version 9.2 by SAS
Institute Inc., Cary NC, USA.Results: A total of 301 patients with pre-dialysis CKD and hypertension were included in this study. The mean age of the study population was 53.5±16.6, and 55% were male. Out of the total 301 patients, 108 (36%) had controlled BP, while 194 (64%) had uncontrolled BP. Overall, 105 patients (35%) were adherent to antihypertension medications, while the remaining 195 (65%) were not adherent. The most common reason for nonadherence was having too many medications to take (65%), followed by forgetfulness (54%), and complex dosing schedule (46%).Conclusion: Adherence to antihypertensive medication is suboptimal among pre-dialysis CKD patients in Saudi Arabia, putting this population at higher risk of CKD progression and cardiovascular events. Large scale studies and quality improvement initiatives and interventions in Saudi Arabia are needed to tackle this problem in order to improve the outcomes of CKD patients with hypertension.

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Published

2025-01-12

How to Cite

MD, M. A. S. (2025). Adherence to Antihypertensive Medications Among Patients with Chronic Kidney Disease in Saudi Arabia: A Single-Center Experience Running title: Adherence to antihypertensive medications in chronic kidney disease patients. South Eastern European Journal of Public Health, 383–388. https://doi.org/10.70135/seejph.vi.3442

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Articles