Formulation and Evaluation of Polyherbal Skin Cream for Wound Healing
DOI:
https://doi.org/10.70135/seejph.vi.3428Abstract
This study sought to develop & assess a herbal skin cream for wound healing, utilizing the inherent restorative qualities of botanical components. Notwithstanding the presence of numerous wound-healing creams, the pace of tissue regeneration continues to be constrained. This study combined contemporary cosmetic technologies with traditional medicinal herbs, including plant extracts such as Azadirachta indica, Sarca indica, Curcuma longa, Glycyrrhiza glabra, & Aloe vera to create a safe & effective product.
The formulation process entailed adjusting the amounts of excipients including sorbitol solution, potassium hydroxide, methylparaben, stearic acid, beeswax, stearyl alcohol, Tween-80, & deionized water. The resultant compositions underwent evaluations of their physical characteristics, encompassing pH, viscosity, spreadability, & stability. The results indicated that the formulations exhibited good consistency, superior spreadability, & no presence of phase separation. The stability measures, such as pH (~6), viscosity, & appearance, exhibited no alterations throughout the three-month testing period done under ICH conditions (40 ± 2 °C & 75 ± 5% RH). The research validated the viability of formulating herbal creams as protective barriers for the skin, exhibiting compatibility with cutaneous secretions. This research underscores the capacity of plant-based formulations to improve wound healing owing to their inherent ability to facilitate tissue repair mechanisms. Subsequent research will further assess the wound-healing effectiveness of these herbal lotions.
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