Evaluation of Rituximab in Immunothrombocytopenia Splenectomized and Non-Splenectomized Patient

Abstract

Stroke carries a high risk of death. Survivors can experience loss of vision and/or speech, paralysis and confusion. The risk of death depends on the type of stroke and its incidence increases with advancing age. Post-stroke aphasia and language impairment are significant health problems among stroke patients and may result in considerable activity limitation. Different types of aphasia might develop according to the location of the stroke.

To identify the types of aphasia in patients with stroke and to assess the relationship between the age and types of aphasia in each type of stroke in those patients.

This was a hospital-based cross-sectional study conducted at Bagdad Teaching Hospital, Medical City and Al Imamin Al Kazmain Medical City during the period from October 2014 to the end of September 2015. One hundred patients were enrolled and assessed at neurology and general medical wards. Clinical assessment of the aphasic patient was performed through clinical and language examination was performed. Statistical analysis was performed using the statistical package for Social Sciences version 22 and the appropriate statistical tests were used accordingly.

The mean age of the studied group was 62.1 ± 13.2 (range: 37-87) years and the majority of the patients aged more than 50 years. Females represented 55% of the patients. Ischemic and hemorrhagic strokes were reported in 76% and 24% of patients, respectively. Global aphasia was found in 32%, Broca´s(17%), Thalamic 17 (17%), Putaminal(11%), and Werneck’s (11%) of the patients, other types were less frequent. Hypertension was the most frequent risk factor reported among the patients Heart failure was the commonest reported cardiac factor. Aphasia was more frequent among patients older than 50 years. No statistically significant association had been found between the age and the types of aphasia (P>0.05). Global, Broca´sWernick´saphasia were significantly associated with ischemic stroke, while Thalamic, Putaminal conduction and anomia were associated with hemorrhagic stroke, (P<0.05). Hyperlipidemia and diabetes mellitus were significantly associated with Ischemic stroke rather than hemorrhagic (P=0.010). Cardiac risk factors were significantly associated with Ischemic stroke, (P = 0.038).7

Aphasia was more frequent with older age, and no significant association had been found between the type of aphasia and the age, generally, no significant association had been found between the types of aphasia and the risk factors, but some types were associated significantly with hypertension, smoking and diabetes mellitus. Further studies are suggested for further assessment.