Detection of the Effect of Platelet-Rich Fibrin on the Management of Dry Socket

Abstract

A dry socket is a commonly seen issue that happens throughout the process of wound healing following a tooth extraction. The etiology of this condition is still limited understood, and it frequently manifests in persons who have a state of good health. As a consequence, the management strategies for dry sockets have always depended on practical experience rather than scientific theory. This study aims to assess the efficacy of platelets-rich fibrin (PRF) in treating dry sockets and compare it with traditional therapy methods.

A randomized controlled clinical trial was conducted among patients with a dry socket, who were categorized into two treatment groups. In the group I, the conventional treatment was used with performing gentle socket curettage and saline irrigation. The group II was treated with platelet-rich fibrin (PRF); the dry socket patients were examined at day 0 and achieved one of two treatment options, then scheduled follow-up appointments on days 4 and 7 after therapy. The pain score, inflammation and tenderness around the socket, and quantity of granulation tissue formation were assessed, respectively.

In total, sixty patients with a dry socket were included in two treatment groups. The results show that The conventional therapy group required more than seven days to reach the same healing phase as group II with PRF-treated socket. It was observed that the PRF-treated group II patients experienced an improvement in pain, tenderness, inflammation and granulation tissue formation.

The sockets treated with PRF showed statistically significant improvement in the healing process and granulation tissue formation compared with conventional treatment.